Clinical Trial

A Study of KN026-based Combination Therapy in HER2-positive Gastric Cancer

Not Yet Recruiting Phase 2/3
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Summary
This study is designed to compare the efficacy and safety of KN026 combined chemotherapy with or without Enlonstobart versus Trastuzumab combined chemotherapy with or without Pembrolizumab as first-line treatment in HER2-positive unresectable locally advanced or metastatic gastric cancer.
Trial Details
NCT Number NCT07332533
Lead Sponsor Shanghai JMT-Bio Inc.
Conditions HER2-positive Gastric Cancer
Enrollment 490 participants
Start Date 2025-12-30
Primary Completion 2032-06-30 (estimated)
Study Completion 2032-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-01-12