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Application of Toripalimab as Adjuvant Therapy After Esophageal Cancer Surgery: A Multicenter Clinical Trial

StatusNot Yet Recruiting
PhasePhase 3
Started2026-01-20
View on ClinicalTrials.gov ↗
This study is a prospective, multicenter, multi-cohort Phase III clinical trial. It primarily enrolls high-risk recurrent esophageal cancer patients who have undergone R0 resection after neoadjuvant chemoimmunotherapy. Eligible patients are stratified based on pathological lymph node status and receive either toripalimab monotherapy as maintenance treatment or clinical observation only.
Trial Details
NCT Number NCT07332221
Lead Sponsor Henan Cancer Hospital
Conditions Esophageal Cancer
Enrollment 435 participants
Start Date 2026-01-20
Primary Completion 2029-10-01 (estimated)
Study Completion 2031-10-01 (estimated)
Updated on ClinicalTrials.gov 2026-01-12