Clinical Trial

Breath Mass Spectrometry in Metabolic Syndrome and Metabolically Healthy Obesity

Recruiting
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Record status
This record was last updated January 9, 2026 (before its estimated June 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
This study aims to develop a non-invasive diagnostic method for metabolic syndrome (MetS) and metabolically healthy obesity (MHO) through analysis of exhaled air. Using proton-transfer-reaction mass spectrometry combined with machine learning algorithms, we will characterize volatile organic compound profiles in 300 participants across three groups: MetS patients, MHO patients, and healthy controls. The primary goal is to create and validate a classification model capable of accurately differentiating these metabolic states based on breath analysis.
Trial Details
NCT Number NCT07330297
Lead Sponsor I.M. Sechenov First Moscow State Medical University
Conditions Metabolic Syndrome, Obesity & Overweight, Metabolically Healthy Obesity
Enrollment 300 participants
Start Date 2024-09-19
Primary Completion 2026-06-01 (estimated)
Study Completion 2026-12-30 (estimated)
Updated on ClinicalTrials.gov 2026-01-09