Clinical Trial

A Study to Evaluate the Effect of Food and Proton Pump Inhibitor on the Pharmacokinetics of ZN-A-1041 in Healthy Participants

Completed Phase 1
View on ClinicalTrials.gov →
Summary
This study is a phase 1, open-label, randomized, four-period crossover study to evaluate the effect of food and rabeprazole on the ZN-A-1041 tablet formulation in healthy male and female participants.
Protocol Amendment History 4 changes
critical Trial completed 2026-05-12
notable Enrollment reduced: 48 -> 24 participants 2026-05-12
notable Primary completion moved earlier: 2026-08-08 -> 2025-12-14 2026-05-12
minor Completion moved earlier: 2026-08-12 -> 2025-12-14 2026-05-12
Trial Details
NCT Number NCT07329972
Lead Sponsor Genentech, Inc.
Conditions Healthy Volunteers
Enrollment 24 participants
Start Date 2025-11-21
Primary Completion 2025-12-14 (estimated)
Study Completion 2025-12-14 (estimated)
Updated on ClinicalTrials.gov 2026-05-11