Clinical Trial

Chrono-ALIGN: A Chronotype-Based Chrono-Nutrition Intervention in Post-Bariatric Patients

Study acronym: Chrono-ALIGN
Not Yet Recruiting
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Summary
This randomized controlled trial will evaluate the impact of chrono-nutrition, a dietary approach that aligns meal timing with the body's circadian rhythms, on weight change, metabolic outcomes, appetite, and gut microbiota in post-bariatric surgery patients. A total of 246 adults who underwent sleeve gastrectomy at least six months earlier will be enrolled at King Saud Medical City. Participants will be randomized to receive either standard post-bariatric nutritional care or personalized chrono-nutrition based on individual chronotype. Outcomes include weight change, metabolic biomarkers, dietary behaviors, sleep patterns, and gut microbiota composition. The study aims to determine whether integrating chrono-nutrition into post-bariatric follow-up can enhance metabolic health and improve long-term health.
Trial Details
NCT Number NCT07324044
Lead Sponsor King Saud University
Collaborators: King Saud Medical City
Conditions Obesity (Disorder), Morbid Obesity, Bariatric Sleeve Gastrectomy, Meal Time, Chronotype, Circadian Rhythm
Enrollment 246 participants
Start Date 2026-01-01
Primary Completion 2027-12-01 (estimated)
Study Completion 2028-12-01 (estimated)
Updated on ClinicalTrials.gov 2026-01-07