Clinical Trial

Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain

Not Yet Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The purpose of this research study is to investigate whether a single administration of psilocybin can improve interoceptive awareness (awareness of bodily sensations) in individuals with chronic low back pain undergoing physical therapy, and whether these improvements are linked to pain relief and better physical therapy outcomes.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-12-24.
Trial Details
NCT Number NCT07306364
Lead Sponsor Yale University
Collaborators: National Center for Complementary and Integrative Health (NCCIH)
Conditions Chronic Low Back Pain (CLBP), Physical Therapy, Psilocybin
Enrollment 45 participants
Start Date 2026-06
Primary Completion 2029-06 (estimated)
Study Completion 2029-06 (estimated)
Updated on ClinicalTrials.gov 2026-07-16