Clinical Trial

BLOOM: Pragmatic Feasibility Trial

Recruiting
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Summary
The goal of this study is to compare two different ways of dosing cefepime, an antibiotic for very sick patients - the usual approach to dosing or a new dosing method. The new dosing method uses only doses that are available in normal care, but choosing between the different doses is based on more information about the patient's body including their kidney function. The primary purpose of this study is to test how easy it is for healthcare professionals to use the new dosing method and how best to conduct the trial. The study will also assess if the new dosing method helps patients recover faster and reduces side effects.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-12-03; most recent amendment 2026-02-04.
Trial Details
NCT Number NCT07287332
Lead Sponsor Mayo Clinic
Conditions Sepsis, Infection
Enrollment 300 participants
Start Date 2026-01-15
Primary Completion 2027-03 (estimated)
Study Completion 2027-07 (estimated)
Updated on ClinicalTrials.gov 2026-02-06