Clinical Trial

Intrathecal Dexmedetomidine-Fentanyl Combination Versus Fentanyl Alone as Adjuvant to Bupivacaine in Spinal Anesthesia for Above Knee Amputation in Sarcomas of Lower Extremity

Recruiting
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Record status
This record was last updated December 11, 2025 (before its estimated April 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
The current work evaluated whether the combination of intrathecal dexmedetomidine and fentanyl provides superior postoperative analgesia to fentanyl alone when administered with hyperbaric bupivacaine.
Trial Details
NCT Number NCT07276867
Lead Sponsor National Cancer Institute, Egypt
Conditions Intrathecal, Dexmedetomidine, Fentanyl, Bupivacaine, Spinal Anesthesia, Above Knee Amputation, Sarcomas, Lower Extremity
Enrollment 58 participants
Start Date 2025-10-20
Primary Completion 2026-04-01 (estimated)
Study Completion 2026-04-01 (estimated)
Updated on ClinicalTrials.gov 2025-12-11