Synthetic Versus Autologous Sling For Stress Incontinence

This is a multi-centre randomized controlled trial comparing mid-urethral synthetic mesh sling or tension-free vaginal tape (TVT) and autologous fascia sling (AFS) in elderly patients with stress predominant urinary incontinence. The investigators aim to investigate new onset pelvic pain 6 months post-op and objective urinary incontinence cure rate 5 years post-op. Secondary objectives include investigation of opioid use, mental health, sexual health, and other post-op outcomes.

NCT Number	NCT07276295
Lead Sponsor	University of British Columbia Collaborators: Canadian Institutes of Health Research (CIHR)
Conditions	Urinary Incontinence
Enrollment	232 participants
Start Date	2026-01-12
Primary Completion	2032-06 (estimated)
Study Completion	2032-12 (estimated)
Updated on ClinicalTrials.gov	2026-01-16