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NCT07268703

Expiratory Muscle Training in Parkinson's Disease With Forward Trunk Flexion

StatusNot Yet Recruiting
PhaseNot applicable
Primary completion (estimated)

At risk: Primary completion moved at least 12 months later.

See at-risk trials from General University Hospital, Prague

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Record History

All 2 versions: 2 with changes below. See every version on ClinicalTrials.gov ↗

  1. Primary completion pushed from Mar 2026 to Apr 2027 Show 5 more changesShow less
    • Start date: Dec 2025 to Feb 2027
    • Eligibility criteria expanded, about 10 words
    • Study completion pushed from May 2026 to Jun 2027
    • Secondary endpoints: details revised at 6 of 6 entries
    • Publications: details revised at 9 of 9 entries
  2. Study First Submitted
  • Notable: the plan changed

Endpoints

Primary

Voluntary peak cough flow
Timeframe: Week -1, week 0, week 4, week 8

Secondary (6)

Assessment of Swallowing
Assessment of Drooling
Maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP)
Forced vital capacity (FVC)
Forced expiratory volume (FEV1)
Show 1 moreShow less
Peak expiratory flow (PEF)

Arms and interventions

PD with Forward Trunk FlexionExperimental

Participants in this arm have Parkinson's disease and forward trunk flexion, defined as thoracic flexion ≥25° or lumbar flexion ≥15° while standing and walking, which completely disappears when lying down. They will follow the study schedule including all assessments and the 4-week EMST program. Outcomes will include voluntary peak cough flow, respiratory muscle strength, swallowing function (FEES), drooling, and posture assessment using standardized photographs.

PD without Forward Trunk FlexionActive comparator

Participants in this arm have Parkinson's disease without forward trunk flexion (no postural abnormalities). They will follow the same study schedule including all assessments and the 4-week EMST program as the experimental group.

Devices: Expiratory muscle strength training

Sites

1 site in 1 country

  • General University HospitalPrague, Czechia