Clinical Trial

Two Post-Operative Pain Protocols at Discharge for Orthopaedic Patients

Recruiting
View on ClinicalTrials.gov →
Summary
This is a single-center, pilot randomized controlled trial designed to evaluate the feasibility of a definitive trial comparing opioid-free discharge prescriptions to usual care (which includes opioids) in patients undergoing major orthopaedic surgery. The main objective is to inform the design and feasibility of the definitive RCT.
Protocol Amendment History 2 changes
notable Primary completion pushed: 2026-04-30 -> 2026-10-30 2026-06-26
minor Completion pushed: 2026-05-31 -> 2026-12-31 2026-06-26
Trial Details
NCT Number NCT07265557
Lead Sponsor Massachusetts General Hospital
Collaborators: McMaster University
Conditions Orthopaedic Related Pain (Musculoskeletal Pain), Opioid, Pain, Pilot Study
Enrollment 100 participants
Start Date 2025-10-06
Primary Completion 2026-10-30 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-06-25