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Aspirin-free Strategy With Ticagrelor in Patients With a Myocardial Infarction Treated Medically Alone

Study acronym: PANTHEON
StatusRecruiting
PhasePhase 3
Started
View on ClinicalTrials.gov ↗

Record History

  1. Start date: Feb 16, 2026 to Mar 3, 2026v4
  2. Trial status: Not Yet Recruiting to Recruiting
    • Start date changed from estimate of Mar 1, 2026 to Feb 16, 2026
    • Site details revised
    v3
  3. Re-verified, no change to tracked fieldsv2
  4. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
In patients with a myocardial infarction (MI) treated medically alone, the objective of the PANTHEON trial is to evaluate if ticagrelor monotherapy reduces bleeding events, without an increase in patient-oriented ischemic events, compared with standard dual antiplatelet therapy (DAPT) with aspirin and ticagrelor for 12 months.
Trial Details
NCT Number NCT07257198
Lead Sponsor Montreal Heart Institute
Conditions
(from sponsor)		 NSTEMI - Non-ST Segment Elevation MI, STEMI (ST Elevation MI), Myocardial Infarction
Related terms Hemorrhage, Myocardial Infarction, Non-ST Elevated Myocardial Infarction, ST Elevation Myocardial Infarction
Enrollment 2,570 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov