Structured Handoff Using Intelligent Framework for Transitions Trial

Inpatient general medicine attendings will be randomized to have an LLM feature turned on to provide a draft of an off-service handoff within Carelign (an EHR-adjacent provider communication tool). Providers who have access to this feature will be clearly instructed that if they use the LLM-generated draft, they must review and edit it as necessary before finalizing. The study will assess measures of documentation burden (as it relates to writing handoff) - including time spent writing handoff - and work exhaustion in both intervention and control groups.

NCT Number	NCT07251907
Lead Sponsor	University of Pennsylvania
Conditions	Electronic Medical Record, Transitions of Care, Physician Workflow, Artificial Intelligence (AI), Large Language Model
Enrollment	85 participants
Start Date	2025-12-15
Primary Completion	2026-04-26 (estimated)
Study Completion	2026-05-11 (estimated)
Updated on ClinicalTrials.gov	2026-06-02