Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult Participants

This study is researching an experimental drug called pozelimab (called "study drug"). The study is focused on people with a condition where certain parts of the eye's retina stop working over time, which can make it harder to see. This is called geographic atrophy (GA). The aim of the study is to see how safe and tolerable the study drug is when used as an injection in the eye. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug * How much study drug is in the blood and the fluid in the eye at different times * Whether the body makes antibodies against the study drug (which could make the drug less effective or could lead to side effects)

NCT Number	NCT07230834
Lead Sponsor	Regeneron Pharmaceuticals
Conditions	Geographic Atrophy (GA)
Enrollment	54 participants
Start Date	2026-01-19
Primary Completion	2028-07-03 (estimated)
Study Completion	2028-07-03 (estimated)
Updated on ClinicalTrials.gov	2026-08-05