Clinical Trial

Fixed-Dose Combinations Pragmatic Randomized Implementation Trial for Blood Pressure Control

Enrolling by Invitation
View on ClinicalTrials.gov →
Summary
The proposed study is an effectiveness-implementation hybrid type II trial designed to evaluate the impact of provider- and patient-directed interventions on FDC use. The trial will test the effectiveness of theory-driven nudges tailored to address provider and patient barriers. All interventions will be pharmacist-driven, with pharmacists delivering information via nudges to providers and via nudges or more intensive interventions (i.e., CPA) to patients. Data to evaluate outcomes will be extracted from electronic health records.
Protocol Amendment History 3 changes
critical Enrolling by invitation only 2026-08-12
notable Primary completion pushed: 2027-03-31 -> 2027-04-30 2026-06-19
minor Completion pushed: 2027-05-31 -> 2027-06-30 2026-06-19
Trial Details
NCT Number NCT07228065
Lead Sponsor Brigham and Women's Hospital
Collaborators: National Institute on Aging (NIA), Wake Forest University Health Sciences
Conditions Hypertension, Primary Care
Enrollment 720 participants
Start Date 2026-08-07
Primary Completion 2027-04-30 (estimated)
Study Completion 2027-06-30 (estimated)
Updated on ClinicalTrials.gov 2026-08-11