Cash Transfers to Pregnant Women With HIV

The goal of this study is to evaluate the effectiveness and implementation of an unconditional cash transfer intervention to improve mental bandwidth, ART adherence, and postpartum retention among pregnant women with HIV in Botswana. The main questions it seeks to answer are: 1. Do unconditional monthly cash transfers improve mental bandwidth relative to usual care among pregnant women with HIV? 2. Do unconditional monthly cash transfers improve ART adherence (PDC) during pregnancy and the postpartum period? 3. Is delivery of UCTs via mobile money feasible and acceptable in public ANC clinics in Botswana? 4. What barriers and facilitators affect implementation, and how should the model be adapted for a larger trial or a policy pilot (e.g., a pregnancy support grant)?

NCT Number	NCT07226492
Lead Sponsor	University of Pennsylvania Collaborators: University of Botswana, National Institute of Mental Health (NIMH)
Conditions	HIV, Pregnancy, HIV Antiretroviral Therapy (ART) Adherence, Post-partum
Enrollment	100 participants
Start Date	2026-03-09
Primary Completion	2028-01-04 (estimated)
Study Completion	2028-01-04 (estimated)
Updated on ClinicalTrials.gov	2026-07-15