Oral Methadone in Cardiac Surgery

Study acronym: OMICS
StatusActive, Not Recruiting
PhasePhase 4
Started

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Trial flagged as At Risk
Primary completion moved at least 2 months later Jun 30, 2026 → Aug 31, 2026
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Record History

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  1. Enrollment closed, study ongoing Show 4 more changesShow less
    • Study completion pushed from Aug 31, 2026 to Oct 31, 2026
    • Primary completion date changed from estimate of Aug 31, 2026 to Aug 22, 2026
    • Eligibility criteria expanded, about 9 words
    • Site details revised
  2. Primary completion pushed from Jun 30, 2026 to Aug 31, 2026
    • Study completion date: Aug 2026 to Aug 31, 2026
    v4
  3. Trial status: Not Yet Recruiting to Recruiting
    • Start date changed from estimate of Jan 1, 2026 to Jan 13, 2026
    • Site details revised
    v3
  4. Secondary endpoints revised (6)v2
  5. Study First Submitted
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Mayo Clinic
1,024 trials monitored
See 128 trials at risk
The purpose of this study is to compare the effects of administration of oral methadone preoperatively and intravenous methadone upon induction of general anesthesia on postoperative pain for patients undergoing elective cardiac surgery.
Trial Details
NCT Number NCT07221617
Lead Sponsor Mayo Clinic
Conditions
(from sponsor)		 Pain, Postoperative, Anesthesia, Cardiac Surgery
Related terms Postoperative Pain
Enrollment 100 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov