Clinical Trial

Oral Methadone in Cardiac Surgery

Study acronym: OMICS
Recruiting Phase 4
View on ClinicalTrials.gov →
Record status
This record was last updated January 14, 2026 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
The purpose of this study is to compare the effects of administration of oral methadone preoperatively and intravenous methadone upon induction of general anesthesia on postoperative pain for patients undergoing elective cardiac surgery.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-10-25; most recent amendment 2026-01-13.
Status change: Not Yet Recruiting → Recruiting 2026-01-13
Trial Details
NCT Number NCT07221617
Lead Sponsor Mayo Clinic
Conditions Pain, Postoperative, Anesthesia, Cardiac Surgery
Enrollment 100 participants
Start Date 2026-01-13
Primary Completion 2026-06-30 (estimated)
Study Completion 2026-08 (estimated)
Updated on ClinicalTrials.gov 2026-01-14