Clinical Trial

Radiation Therapy (RT) for Parkinson's Disease (PD)

Enrolling by Invitation
View on ClinicalTrials.gov →
Summary
The purpose of this study is to investigate the use of ultra-low, anti-inflammatory doses of radiation therapy (RT) for the treatment of Parkinson's Disease (PD). In this study, the TrueBeam LINAC utilizes a linear accelerator (LINAC) for the delivery of radiation therapy. Dynamic conformal arc (DCA) therapy will be used to deliver a total of five (5) once-a-day radiation treatments (RT) using DaT-SPECT (Dopamine Transporter-Single-Photon Emission Computed Tomography) and MRI imaging to guide radiation treatment planning.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2025-10-17; most recent amendment 2026-06-15.
Status change: Recruiting → Enrolling by Invitation 2025-10-23
Trial Details
NCT Number NCT07218952
Lead Sponsor Mayo Clinic
Conditions Parkinson's Disease
Enrollment 20 participants
Start Date 2026-01-20
Primary Completion 2027-10 (estimated)
Study Completion 2027-10 (estimated)
Updated on ClinicalTrials.gov 2026-06-16