Clinical Trial

A Study of REGN7041 for Active Noninfectious Uveitis in Adult Participants

Study acronym: TITAN
Active, Not Recruiting Phase 1/2
View on ClinicalTrials.gov →
Summary
This study is researching an experimental drug called REGN7041 (also referred to as "study drug"). The study is focused on patients who have active inflammation inside of the eye without any signs of infection. The aim of the study is to see how safe and tolerable the study drug is. This is the first time the study drug is being tested in humans. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug * How much study drug is in the blood and the fluid in the eye at different times * Whether the body makes antibodies against the study drug (which could make the study drug less effective or could lead to side effects)
Protocol Amendment History 1 change
critical Trial status changed: Recruiting → Active, Not Recruiting 2026-04-23
Trial Details
NCT Number NCT07218770
Lead Sponsor Regeneron Pharmaceuticals
Conditions Active Noninfectious Uveitis Affecting the Posterior Segment
Enrollment 72 participants
Start Date 2025-12-17
Primary Completion 2028-06-28 (estimated)
Study Completion 2028-06-28 (estimated)
Updated on ClinicalTrials.gov 2026-04-22