Clinical Trial

A Study to Investigate the Effect of AZD0780 on Metformin Pharmacokinetics in Healthy Adult Volunteers Aged 18 to 55 Years

Completed Phase 1
View on ClinicalTrials.gov →
Summary
The purpose of this study is to determine how the experimental medication AZD0780 impacts the pharmacokinetics (PK) of metformin, a common medication used to treat type 2 diabetes mellitus, when given together in healthy participants.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-10-10; most recent amendment 2026-01-08.
Status change: Active, Not Recruiting → Completed 2026-01-08
Status change: Recruiting → Active, Not Recruiting 2025-12-17
Status change: Not Yet Recruiting → Recruiting 2025-12-05
Trial Details
NCT Number NCT07216131
Lead Sponsor AstraZeneca
Collaborators: Parexel
Conditions Healthy Participants
Enrollment 14 participants
Start Date 2025-11-10
Primary Completion 2025-12-30 (estimated)
Study Completion 2025-12-30 (estimated)
Updated on ClinicalTrials.gov 2026-01-09