Clinical Trial

Metabolic Effects of Short-term Ultra-processed Food Intake (MEST-UPF)

Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated December 15, 2025 (before its estimated April 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
The overall aim of this project is to study the effects of short-term high ultra-processed food intake, compared to nutrient- and energy density matched low ultra-processed food (UPF) intake, on energy intake and appetite. A total of 24 men and women who meet all inclusion criteria and none of the exclusion criteria will be invited to participate. A randomized 2\*2 factorial four-way crossover study will be conducted at the Department of Internal medicine and Clinical Nutrition at the University of Gothenburg, comparing a high-UPF meal to a low-UPF meal also with high and/or low energy density. A supervised breakfast meal will be served, and postprandial blood samples and appetite measures will be collected continuously up to 4 hours after the breakfast meal. Subsequently, an ad libitum lunch meal will be served, and energy intake will be recorded.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-10-01; most recent amendment 2025-12-12.
Status change: Not Yet Recruiting → Recruiting 2025-11-25
Trial Details
NCT Number NCT07213245
Lead Sponsor Göteborg University
Conditions Appetite, Obesity and Obesity-related Medical Conditions
Enrollment 24 participants
Start Date 2025-12-01
Primary Completion 2026-04-30 (estimated)
Study Completion 2026-04-30 (estimated)
Updated on ClinicalTrials.gov 2025-12-15