Clinical Trial

Efavirenz (EFV) Intensification

Completed Phase 4
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial is to see if Efavirenz (EFV) intensification to a baseline combination antiretroviral regimen (cART) can help reduce the size of the latent reservoir in people living with HIV (PLWH). The main questions this study aims to address are: 1. is the addition of EFV to a cART regimen safe and well tolerated? 2. Is there a reduction in the blood and tissue HIV reservoir after intensification? Researchers will compare each participants reservoir size prior to and post EFV intensification.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2025-09-22; most recent amendment 2026-06-22.
Trial Details
NCT Number NCT07193875
Lead Sponsor Washington University School of Medicine
Conditions HIV
Enrollment 9 participants
Start Date 2023-02-09
Primary Completion 2024-12-16 (estimated)
Study Completion 2024-12-16 (estimated)
Updated on ClinicalTrials.gov 2026-07-17