Clinical Trial

Clinical and Biological Signs of Dapagliflozin Overdose in ICU Patients With Metformin Poisoning

Recruiting
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Record status
This record was last updated September 25, 2025 (before its estimated April 11, 2026 completion). Its status may not reflect the trial's current state.
Summary
This study looks at patients admitted to intensive care for drug poisoning involving metformin, a common diabetes medication. Researchers will compare two groups: patients who overdosed on metformin alone and those who took both metformin and dapagliflozin, another diabetes drug. The goal is to find clinical or laboratory signs that could help doctors quickly recognize a dapagliflozin overdose in this context, which could improve treatment and patient outcomes.
Trial Details
NCT Number NCT07193069
Lead Sponsor Centre Hospitalier de Saint-Denis
Conditions Drug Overdose, Metformin, Dapagliflozin, Lactic Acidosis, Diabetic Ketoacidosis, Intensive Care Units
Enrollment 50 participants
Start Date 2025-04-11
Primary Completion 2026-04-11 (estimated)
Study Completion 2026-04-11 (estimated)
Updated on ClinicalTrials.gov 2025-09-25