Clinical Trial

Assessment of the Dose Safety and Efficacy of Serine Combined With Fluorouracil Drugs

Not Yet Recruiting Phase 1
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Record status
This record was last updated September 17, 2025 (before its estimated February 2026 completion). Its status may not reflect the trial's current state.
Summary
This study evaluates the dose safety and efficacy of serine in combination with fluoropyrimidine-based therapies. Primary objective: To determine the safety of oral serine administration. Secondary objectives: 1. To assess the preliminary efficacy of serine in the study population. 2. To establish the recommended Phase 2 dose for oral serine.
Trial Details
NCT Number NCT07178613
Lead Sponsor The First Affiliated Hospital of Xinxiang Medical College
Conditions Advanced Colorectal Cancer
Enrollment 20 participants
Start Date 2025-11
Primary Completion 2026-02 (estimated)
Study Completion 2026-02 (estimated)
Updated on ClinicalTrials.gov 2025-09-17