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Azithromycin Versus Doxycycline in Hospitalized Adult Patients With Community Acquired Pneumonia Treated With Beta-lactams

Study acronym: AD-CAP
StatusRecruiting
PhasePhase 4
Started2025-09-15
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary endpoint reworded 1 of 1 changed
See other at-risk trials from Mayo Clinic

Amendment history

2026-09-25
Primary endpoint(s) modified1 entry, revised
WasHospital-free days
NowDays alive and out of hospital
2026-07-01
Study Status, IPDSharing v2
Re-verified, no change to tracked fields
2025-10-06
Not Yet Recruiting→Recruiting Study Identification, Study Status, Contacts/Locations v1
Trial statusNot Yet Recruiting→Recruiting
Start dateestimated 2025-09-30→confirmed 2025-09-15
Study sitesdetails revised at 5 of 5 sites
Study title+26 characters
Azithromycin Versus Doxycycline in Hospitalized Adult Patients With Community Acquired Pneumonia Treated With Beta-lactams
2025-09-05
Original filing
Mayo Clinic
1,015 trials monitored
See 115 trials at risk
The purpose of this study is to compare effectiveness and safety of Azithromycin versus Doxycycline in adult patients hospitalized with community acquired pneumonia (CAP) treated with Beta-lactams.
Trial Details
NCT Number NCT07164131
Lead Sponsor Mayo Clinic
Collaborators: National Heart, Lung, and Blood Institute (NHLBI)
Conditions Community-acquired Pneumonia
Enrollment 1,120 participants
Start Date 2025-09-15
Primary Completion 2030-09-01 (estimated)
Study Completion 2031-09-01 (estimated)
Updated on ClinicalTrials.gov 2026-09-24