Advanced Fibrosis Detection for MASLD in Primary Care

This proposal evaluates the implementation of a novel, non-interruptive, electronic health record alert for metabolic dysfunction-associated steatotic liver disease (MASLD) fibrosis risk assessment in primary care patients with MASLD using a stepped wedge, cluster randomized design. This work will generate generalizable data to dramatically enhance MASLD management in primary care.

NCT Number	NCT07159386
Lead Sponsor	Medical University of South Carolina Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH)
Conditions	Metabolic Dysfunction-associated Steatotic Liver Disease
Enrollment	225 participants
Start Date	2026-03-16
Primary Completion	2030-09 (estimated)
Study Completion	2030-09 (estimated)
Updated on ClinicalTrials.gov	2026-03-31