Clinical Trial

Long Term Effect of Brain Stimulation in PPA

Study acronym: RECONNECT-PLUS
Recruiting
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial is to investigate the effect of non-invasive brain stimulation techniques in the progression of primary progressive aphasia for 6 months. We will compare three modalities of brain stimulation (TMS, tDCS, TMS+tDCS) against sham stimulation. All patients will receive also language therapy.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-08-28; most recent amendment 2026-04-19.
Status change: Not Yet Recruiting → Recruiting 2025-09-04
Trial Details
NCT Number NCT07158216
Lead Sponsor Hospital San Carlos, Madrid
Conditions Primary Progressive Aphasia(PPA)
Enrollment 80 participants
Start Date 2025-09-15
Primary Completion 2028-12 (estimated)
Study Completion 2028-12 (estimated)
Updated on ClinicalTrials.gov 2026-04-23