Identification of New Non-invasive, Predictive, and Diagnostic Biomarkers for Colorectal Cancer

The study in question is an observational study that aims to identify new non-invasive biomarkers present in the serum of patients with CRC and, subsequently, to create a score capable of predicting the development of CRC. It is an observational study with 3 enrollment arms: Arm 1: Patients undergoing surgery at the U.O.C. of Surgery, with a CRC diagnosis; Arm 2: Subjects with a negative result from the endoscopic examination; Arm 3: Subjects in whom the presence of an adenoma with high-grade dysplasia is found, a condition considered pre-cancerous.

NCT Number	NCT07153458
Lead Sponsor	Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis Collaborators: University of Bari Aldo Moro
Conditions	CRC (Colorectal Cancer), Adenoma Colon
Enrollment	60 participants
Start Date	2025-12-01
Primary Completion	2026-12-01 (estimated)
Study Completion	2027-12-01 (estimated)
Updated on ClinicalTrials.gov	2025-12-19