Clinical Trial

Transcranial Magnetic Stimulation and Psychotherapy for Treating Obsessive-Compulsive Disorder

Recruiting
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Summary
This study will test how people with OCD respond to a type of noninvasive brain stimulation, repetitive Transcranial Magnetic Stimulation (rTMS), when it is combined with psychotherapy. Participants will either engage in Exposure and Response Prevention (ERP) Therapy or supportive therapy (ST) while receiving rTMS. Biobehavioral data from wearable devices and smartphones will be collected to better predict treatment responses. Participants will also undergo repeat resting state functional Magnetic Resonance Imaging (rsfMRI) in order to assess neural predictors and mechanisms of treatment response.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-08-20; most recent amendment 2025-10-23.
Status change: Not Yet Recruiting → Recruiting 2025-10-23
Trial Details
NCT Number NCT07146438
Lead Sponsor Adam Frank
Conditions Obsessive - Compulsive Disorder
Enrollment 48 participants
Start Date 2025-11-10
Primary Completion 2028-06 (estimated)
Study Completion 2028-08 (estimated)
Updated on ClinicalTrials.gov 2025-10-27