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Transcranial Magnetic Stimulation and Psychotherapy for Treating Obsessive-Compulsive Disorder

StatusRecruiting
PhaseNot applicable
SponsorAdam Frank
Started
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Record History

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  1. Trial status: Not Yet Recruiting to Recruiting
    • Start date: Sep 15, 2025 to Nov 10, 2025
    • Site details revised
    v4
  2. Re-verified, no change to tracked fieldsv3
  3. Start date: Aug 25, 2025 to Sep 15, 2025v2 Show 6 more changesShow less
    • Interventions: Exposure and Response Prevention (ERP) Therapy (Behavioral), Supportive Therapy (ST) (Behavioral), TMS (Device) to Exposure and Response Prevention (ERP) Therapy (Behavioral), Repetitive Transcranial Magnetic Stimulation (rTMS) (Device), Supportive…
    • Eligibility criteria expanded, about 11 words
    • Secondary endpoints: details revised at 4 of 7 entries
    • Primary endpoint revised
    • Site contact updated
    • Study title expanded, about 1 word
  4. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Adam Frank
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This study will test how people with OCD respond to a type of noninvasive brain stimulation, repetitive Transcranial Magnetic Stimulation (rTMS), when it is combined with psychotherapy. Participants will either engage in Exposure and Response Prevention (ERP) Therapy or supportive therapy (ST) while receiving rTMS. Biobehavioral data from wearable devices and smartphones will be collected to better predict treatment responses. Participants will also undergo repeat resting state functional Magnetic Resonance Imaging (rsfMRI) in order to assess neural predictors and mechanisms of treatment response.
Trial Details
NCT Number NCT07146438
Lead Sponsor Adam Frank
Conditions
(from sponsor)		 Obsessive - Compulsive Disorder
Related terms Compulsive Personality Disorder, Mental Disorders, Obsessive-Compulsive Disorder
Enrollment 48 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov