Clinical Trial

Metyrapone Study for Patients Diagnosed With Mild Autonomous Cortisol Secretion - MACS

Name: Metyrapone Study for Patients Diagnosed With Mild Autonomous Cortisol Secretion - MACS — clinical trial record (NCT07138274)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Not Yet Recruiting Phase 2

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Summary

single-center, randomized, double-blind, placebo-controlled Phase 2 study to evaluate safety and efficacy of overnight metyrapone in patients with MACS.

Protocol Amendment History 1 amendment

This ClinicalTrials.gov record has been amended once since 2025-08-17.

Trial Details

NCT Number	NCT07138274
Lead Sponsor	Mayo Clinic
Conditions	Mild Autonomous Cortisol Secretion (MACS), Autonomous Cortisol Secretion (ACS)
Enrollment	90 participants
Start Date	2026-08
Primary Completion	2031-06 (estimated)
Study Completion	2031-12 (estimated)
Updated on ClinicalTrials.gov	2026-06-29