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Aromatherapy Essential Oils to Manage Anxiety and Nausea in Cancer Patients Receiving Infusion in the Ambulatory Setting

StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 6 months later Jan 1, 2027 → Jul 14, 2027
See other at-risk trials from City of Hope Medical Center

Record History

See every version on ClinicalTrials.gov ↗

  1. Notable Primary and study completion pushed from Jan 1, 2027 to Jul 14, 2027
    • Start date: Jul 8, 2025 to Aug 6, 2025
    • Eligibility criteria expanded, about 15 words
    • Secondary endpoints: details revised at 2 of 3 entries
  2. Notable Recruitment resumed after suspension
    • Site details revised at 2 of 2 sites
    v3
  3. Stopped Trial status: Recruiting to Suspended Sponsor's reason: Study suspended pending analysis of the ginger aromatherapy arm. The hold may be lifted once the analysis is complete and amendment, if…
    • Site details revised at 2 of 2 sites
    v2
  4. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This clinical trial tests how well aromatherapy essential oils work to manage anxiety and nausea in cancer patients receiving infusions in the ambulatory setting. Current drugs that are given for nausea may cause constipation and fatigue. Therefore, there is interest in exploring complementary therapies, like aromatherapy, that do not carry the same side effects. Using aromatherapy essential oils such as ginger, peppermint, and lavender, may help reduce nausea and anxiety. Some studies have shown significant reductions in nausea and anxiety among cancer patients using these oils, while other studies have had mixed results. Ginger and peppermint oils, in particular, have been associated with helping reduce nausea during chemotherapy, while lavender has shown potential benefits for anxiety. Jojoba oil will be used as a placebo for this research study. Jojoba oil is extracted from the seeds of a jojoba plant, which is a green shrub that is found in the southwestern United States). Jojoba oil is an oil which has no color or smell. Aromatherapy essential oils used through a personal inhalation device during chemotherapy may better manage anxiety and nausea in cancer patients receiving infusions in the ambulatory setting.
Trial Details
NCT Number NCT07126301
Lead Sponsor City of Hope Medical Center
Collaborators: National Cancer Institute (NCI)
Conditions
(from sponsor)
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Enrollment 60 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov