Impact of an Electronic Health Record Maintenance Alert on PSA Screening Rates in a 10-Hospital Integrated Health System

\- The investigators propose a clinical trial to evaluate the impact of annual shared decision making for PSA screening, supported by system-level enhancements to promote evidence-based care: * Defined referral thresholds within the health maintenance reminder, aligned with clinical risk stratification per NCCN guidelines. * Enhanced clinical decision support (CDS) tools to reduce provider variation and ensure guideline-concordant screening and referral practices. * The goal is to reduce late-stage presentation without increasing overdiagnosis-ensuring that prostate cancer screening is both accessible and clinically effective.

NCT Number	NCT07109427
Lead Sponsor	Washington University School of Medicine
Conditions	Prostate Cancer, Cancer of the Prostate
Enrollment	40,000 participants
Start Date	2025-08-11
Primary Completion	2031-08-31 (estimated)
Study Completion	2031-08-31 (estimated)
Updated on ClinicalTrials.gov	2025-08-17