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Aerobic Exercise and Obsessive-Compulsive Disorder Symptoms

StatusRecruiting
PhaseNot applicable
Started2026-02-16
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 12 months later Sep 1, 2026 → Sep 1, 2027
See other at-risk trials from Yale University

Amendment history

2026-09-30
critical
Primary completion pushed: 2026-09-01 → 2027-09-01
Completion pushed: 2026-09-01 → 2027-09-01
2026-06-30
notable
Not Yet Recruiting→Recruiting Study Status, Contacts/Locations v2
Trial statusNot Yet Recruiting→Recruiting
Start dateestimated 2025-12-01→confirmed 2026-02-16
Study sitesdetails revised at 1 of 1 site
2025-11-06
minor
Study Status v1
Start date2025-09-01→2025-12-01
2025-07-31
minor
Original filing
487 trials monitored
See 35 trials at risk
The purpose of this study is to examine the acute effects of exercise on cognitive flexibility and symptom reactivity. The main questions it aims to answer are: Does moderate intensity physical activity reduce subjective distress, compulsive urges, and intrusions- and increase cognitive flexibility- in adults with obsessive-compulsive disorder compared to low-intensity physical activity? Researchers will compare low- to moderate-intensity exercise to see if moderate physical activity increases cognitive flexibility and reduces symptom reactivity in adults with obsessive-compulsive disorder (OCD). Participants will: Complete self-report surveys, psychiatric interviews, and cognitive tasks. Be assigned to either a low- or moderate-intensity exercise condition and complete physical activity. Repeat cognitive and symptom measures following the exercise intervention.
Trial Details
NCT Number NCT07103902
Lead Sponsor Yale University
Conditions Obsessive-Compulsive Disorder (OCD)
Enrollment 50 participants
Start Date 2026-02-16
Primary Completion 2027-09-01 (estimated)
Study Completion 2027-09-01 (estimated)
Updated on ClinicalTrials.gov 2026-09-29