Clinical Trial

Effects of Isocapnic Respiratory Muscle Endurance Training in Healthy Adults

Recruiting

Record status

This record was last updated May 15, 2026 (before its estimated August 1, 2026 completion). Its status may not reflect the trial's current state.

Summary

Respiratory muscle training (RMT) strengthens breathing muscles and may improve exercise performance and reduce breathlessness. However, different training methods and devices create controversy in the field. Two main types of RMT exist: inspiratory muscle training (IMT) and respiratory endurance training, like voluntary isocapnic hyperpnea (VIH). While IMT is well-studied, the impact of VIH on breathlessness remains unclear. This study will use the Canadian-developed BreathWayBetter device to examine how 5 weeks of VIH affects breathing discomfort and muscle function. Findings may help personalize RMT for athletes and clinical patients, improving respiratory care and exercise tolerance.

Protocol Amendment History 2 amendments

This ClinicalTrials.gov record has been amended 2 times since 2025-07-31; most recent amendment 2026-05-13.

Status change: Not Yet Recruiting → Recruiting 2026-05-13

Trial Details

NCT Number	NCT07103291
Lead Sponsor	University of British Columbia Collaborators: Mitacs
Conditions	Healthy Adults
Enrollment	32 participants
Start Date	2025-08-04
Primary Completion	2026-08-01 (estimated)
Study Completion	2026-08-01 (estimated)
Updated on ClinicalTrials.gov	2026-05-15