Enhancing Resilience Among Patients With Stroke: Implementation of High Intensity Home-based Rehabilitation

The goal of this observational study is to test whether a model of high-intensity home-based rehabilitation (HIHR) helps patients get good outcomes after treatment for a stroke at Duke University Hospital. The main question it aims to answer is: Do patients who receive HIHR services after their stroke recover their function at least as well as patients who discharge to an inpatient rehabilitation facility? Participants will not be assigned to any group. Rather, patients who choose to discharge from the hospital to their home and receive HIHR services after their stroke will be enrolled in the study so that researchers can compare their outcomes to those for other patients who instead discharged to an inpatient rehabilitation facility.

NCT Number	NCT07098286
Lead Sponsor	Duke University Collaborators: Claude D. Pepper Older American Independence Centers (OAICS), Agency for Healthcare Research and Quality (AHRQ)
Conditions	Stroke, Stroke Rehabilitation
Enrollment	500 participants
Start Date	2025-08-25
Primary Completion	2026-08-31 (estimated)
Study Completion	2028-07-31 (estimated)
Updated on ClinicalTrials.gov	2026-08-05