Clinical Trial

Effect of Ketone Esters on Liver Fat Content and Metabolic Function

Study acronym: JV
Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial is to determine whether ingestion of a ketone ester drink helps improve liver health and blood glucose control. Ketones are a type of energy source made by the body during times of weight loss, low carbohydrate intake and starvation. People enrolled in this study will be randomly assigned (by chance, like the flip of a coin) to one of two groups: Group 1: Ketone ester drink consumed daily for 6 weeks. Group 2: Placebo drink consumed daily for 6 weeks.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-07-24; most recent amendment 2026-07-13.
Status change: Not Yet Recruiting → Recruiting 2025-08-14
Trial Details
NCT Number NCT07097506
Lead Sponsor Washington University School of Medicine
Collaborators: Children's Discovery Institute
Conditions MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Obesity, Overweight (BMI > 25)
Enrollment 40 participants
Start Date 2025-09-26
Primary Completion 2027-07-31 (estimated)
Study Completion 2027-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-07-15