Parkinson's Research In Metagenomic Early Stage Biomarkers

This 2x2 factorial, randomized, controlled pilot study aims to identify a specific microbiota pattern, which could constitute a biomarker of Parkinson's disease, and to evaluate whether specific pathotypes can be associated with different stages of the disease; furthermore, the investigators are committed to evaluating how and to what extent the changes induced by a personalized nutritional intervention combined with physical exercise affect the symptoms and quality of life of patients.

NCT Number	NCT07097103
Lead Sponsor	IRCCS San Raffaele Roma Collaborators: San Raffaele Telematic University, University of Urbino "Carlo Bo", Northwestern University
Conditions	Parkinson's Disease (PD)
Enrollment	80 participants
Start Date	2026-09-01
Primary Completion	2029-07-11 (estimated)
Study Completion	2029-07-31 (estimated)
Updated on ClinicalTrials.gov	2026-07-30