Clinical Trial

Clinical Study of the Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of BCD-261 in Subjects With Moderate to Severe Active Crohn's Disease

Study acronym: COMANDOR
Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The aim of the study is to evaluate the efficacy, safety, pharmacokinetics, pharmacodynamics and immunogenicity of study drug (BCD-261) in comparison with placebo and to characterize the dose-response relationship in patients with moderate to severe active Crohn's Disease. The study will be conducted in a population of male and female subjects ≥18 years and ≤75 years with moderate to severe active Crohn's Disease and an inadequate response to prior treatment with glucocorticoids, immunosuppressants, or biologics/targeted immunosuppressants.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-07-14; most recent amendment 2025-09-16.
Trial Details
NCT Number NCT07078994
Lead Sponsor Biocad
Conditions Crohn's Disease (CD)
Enrollment 204 participants
Start Date 2025-08-14
Primary Completion 2027-05 (estimated)
Study Completion 2029-01 (estimated)
Updated on ClinicalTrials.gov 2025-09-17