Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation

The goal of this clinical research study is to learn about the safety and effects of M032 given directly into the tumor in children and adults with DMG and who have received standard-of-care radiation therapy.

NCT Number	NCT07076498
Lead Sponsor	M.D. Anderson Cancer Center Collaborators: Congressionally Directed Medical Research Programs
Conditions	Glioma
Enrollment	20 participants
Start Date	2026-04-23
Primary Completion	2029-12-31 (estimated)
Study Completion	2031-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-07-30