Healthy Living BEYOND Weight Study

The Healthy Living BEYOND Weight Study is an observational research study of participants living with overweight and obesity. The principal objectives for this project will be to answer fundamental unanswered questions regarding patient experiences and outcomes related to overweight and obesity, and to assess the real-world effectiveness of different weight management strategies, within contemporary and diverse populations. To accomplish this, the Study Team for this project will leverage their expertise in the science of obesity and cardiometabolic health; epidemiology, cohort and registry studies; implementation science; cardiovascular prevention and management; and disparities and community-based research to lead the development of an innovative cohort of people living with overweight or obesity with two key components: 1. patient-report data elements, obtained through surveys; 2. linkage to EHR records providing data regarding clinical encounters. The cohort will be inclusive, comprehensive, and constructed with scientific rigor as well as high internal and external validity. An overall objective is for the Healthy Living BEYOND Weight Study is to serve as an enduring resource for researchers studying the health consequences of obesity and evaluating the impact of weight management strategies.

NCT Number	NCT07075341
Lead Sponsor	American Heart Association Collaborators: Evidation Health, Duke Clinical Research Institute, Johns Hopkins University
Conditions	Overweight or Obesity
Enrollment	1,000,000 participants
Start Date	2025-06-30
Primary Completion	2060-12 (estimated)
Study Completion	2060-12 (estimated)
Updated on ClinicalTrials.gov	2025-08-06