Clinical Trial

A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma, GHoST Trial

Recruiting
View on ClinicalTrials.gov →
Summary
This clinical trial tests how well a digital treatment platform using a mobile application works for the delivery of home-based sequential therapy in patients with glioma. Access to specialized neuro-oncology care in the United States for patients with glioma is critically deficient. Care at centers with neuro-oncology specialists is associated with improved survival outcomes, yet many patients have limited access due to distance, disease-related disability, or lack of financial resources. The application provides patients continuous access to their care team in the home setting. A digital treatment platform may increase clinical trial participation and accelerate development of novel therapeutics while addressing a great health disparity in patients with glioma.
Protocol Amendment History 3 changes
critical Primary endpoint(s) modified 2026-08-11
notable Enrollment increased: 120 -> 202 participants 2026-08-11
minor Trial arms changed: 1 -> 3 2026-08-11
Trial Details
NCT Number NCT07074756
Lead Sponsor Mayo Clinic
Conditions Glioma, Recurrent Glioma, Recurrent Glioblastoma
Enrollment 202 participants
Start Date 2025-09-12
Primary Completion 2028-08-31 (estimated)
Study Completion 2028-08-31 (estimated)
Updated on ClinicalTrials.gov 2026-08-10