Clinical Trial

Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA

Name: Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA — clinical trial record (NCT07070466)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Recruiting Phase 2

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Summary

This is a single arm, open-label, phase II trial investigating the combination of ivonescimab with standard FOLFOX chemotherapy in 1L therapy for HER2- GEA.

Protocol Amendment History 1 amendment

This ClinicalTrials.gov record has been amended once since 2025-07-07.

Status change: Not Yet Recruiting → Recruiting 2026-03-04

Trial Details

NCT Number	NCT07070466
Lead Sponsor	Massachusetts General Hospital Collaborators: Summit Therapeutics
Conditions	Stomach Cancer Stage IV, Esophagus Cancer, Stomach Cancer
Enrollment	40 participants
Start Date	2025-10-10
Primary Completion	2026-12-01 (estimated)
Study Completion	2028-09-01 (estimated)
Updated on ClinicalTrials.gov	2026-03-06