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Mortality Outcome of Controlled Blood Pressure Participants

Study acronym: HTN-Mort
StatusCompleted
PhaseNot specified
Started
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Record History

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  1. Trial completed Show 4 more changesShow less
    • Final enrollment: 246587 participants (planned 100)
    • Primary completion date changed from estimate of Dec 31, 2026 to Sep 29, 2026
    • Study description revised
    • Eligibility criteria expanded, about 2 words
  2. Re-verified, no change to tracked fieldsv8
  3. Study title shortened, about 3 wordsv7
  4. Trial status changed: Recruiting → Active, Not Recruiting
    • Site details revised
    v6
  5. Study description shortened, about 1 wordv5
Show 3 earlier versionsHide 3 earlier versions
  1. Primary completion date: Dec 31, 2025 to Dec 31, 2026
    • Study completion date: Feb 1, 2026 to Feb 1, 2027
    v4
  2. Primary completion date: Sep 1, 2025 to Dec 31, 2025
    • Study completion date: Oct 1, 2025 to Feb 1, 2026
    v3
  3. Site contact updated
    • Study title shortened, about 10 words
    • Study arms: 1 to 2
    v2
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Despite advances in antihypertensive therapy, some patients with well-controlled blood pressure still experience fatal outcomes. This paradox raises critical questions about the efficacy of blood pressure-targeted interventions and whether BP control alone ensures survival. This systematic review and meta-analysis aims to evaluate all-cause mortality and cardiovascular death among hypertensive patients who achieved BP targets in RCTs or open-label trials. To determine whether achieving controlled blood pressure through intentional intervention (pharmacological or procedural) in RCTs or open-label studies reduces mortality (all-cause and cardiovascular) in hypertensive patients.
Trial Details
NCT Number NCT07067632
Lead Sponsor DejthidaNathaphong
Conditions
(from sponsor)		 Valid MeSH Conditions, Hypertension (HTN)
Related terms Hypertension
Enrollment 246,587 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov