Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT07004972 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

A Study of Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)

StatusActive, Not Recruiting
PhasePhase 4
Started2025-09-04
View on ClinicalTrials.gov ↗

Amendment history

2026-04-23
Study Identification, Study Status, Eligibility, Contacts/Locations, References v7
Trial status changed: Recruiting → Active, Not Recruiting
Trial sites reduced: 31 → 24 locations
Eligibility criteria-21 characters
[...] adient ≥ 50 mmHg during screening as assessed by TTE at rest, or with Valsalva maneuver, or post exercise LVOT peak gradient. Has LVOT peak gradient with Valsalva maneuver at screening TTE of ≥ 30 mmHg. Has adequate acoustic window [...]
2026-03-02
Study Status, Contacts/Locations, IPDSharing v6
Study sites29→31
2026-01-28
Study Status, Contacts/Locations v5
Study sites27→29
2025-11-19
Study Status, Contacts/Locations v4
Study sites27 entries, revised
Marengo CIMS Hospital Amrita Institute Of Medical Sciences And Research CentreHospital All India Institute of Medical Sciences Sir (Ganga AIIMSRam ) - Nagpur Local Institution - 0005Hospital
2025-10-27
Study Status, Contacts/Locations v3
Study sites25→27
Show 2 earlier versions
2025-09-19
Not Yet Recruiting→Recruiting Study Status, Contacts/Locations v2
Trial statusNot Yet Recruiting→Recruiting
Start dateestimated 2025-08-18→confirmed 2025-09-04
Study sites25 entries, revised
LocalOsmania InstitutionGeneral -Hospital Unicare 0014Heart Institute (A division of Unique Hospital) LocalMedanta InstitutionHeart -Institute KLES 0006Dr. Prabhakar Kore Hospital & M.R.C LocalOmega InstitutionHospital Laxmipat -Singhania 0020 LocalInstitute Institutionof - 0004 Local Institution - 0008 Local Institution - 0023Cardiology
2025-07-14
Study Status, References v1
Start date2025-06-30→2025-08-18
2025-05-26
Original filing
The purpose of this study is to evaluate the safety, tolerability and effectiveness of mavacamten in adults with obstructive hypertrophic cardiomyopathy in India.
Trial Details
NCT Number NCT07004972
Lead Sponsor Bristol-Myers Squibb
Conditions Symptomatic Obstructive Hypertrophic Cardiomyopathy
Enrollment 50 participants
Start Date 2025-09-04
Primary Completion 2027-12-13 (estimated)
Study Completion 2027-12-13 (estimated)
Updated on ClinicalTrials.gov 2026-04-28