EEG Evaluation of CBT for Obsessive-Compulsive Disorder

This clinical trial investigates how Cognitive Behavioral Therapy (CBT), a psychological treatment that helps people change their thought and behavior patterns, affects brain function in people diagnosed with Obsessive-Compulsive Disorder (OCD). OCD is characterized by repeated, unwanted thoughts (obsessions) and behaviors (compulsions) that significantly interfere with daily life. Although CBT is known to effectively reduce OCD symptoms, exactly how it changes brain activity remains unclear. This study aims to measure the effects of CBT on brain function using electroencephalography (EEG), a safe, non-invasive way to monitor brain activity. Participants diagnosed with OCD will be randomly assigned to two groups. One group will receive CBT consisting of 12 individual therapy sessions, held weekly, lasting about 50 minutes each. The other group will not receive therapy during the study but will be offered treatment afterward. Brain activity and psychological well-being will be measured three times: before starting treatment, immediately after completing CBT, and again three months later. By comparing these two groups, the study hopes to answer whether CBT causes measurable changes in brain activity and how these changes relate to improvements in OCD symptoms. Results from this study could help improve future treatments and understanding of OCD.

NCT Number	NCT07000812
Lead Sponsor	Uskudar University Collaborators: Istanbul Nisantasi University, Beykoz University
Conditions	Obsessive-Compulsive Disorder
Enrollment	60 participants
Start Date	2025-01-01
Primary Completion	2025-09-30 (estimated)
Study Completion	2025-10-25 (estimated)
Updated on ClinicalTrials.gov	2025-06-03