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Head and Neck Cancer Study Project in the Geriatric Population

StatusRecruiting
PhasePhase 3
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 6 months later Jun 1, 2026 → Dec 1, 2026
See other at-risk trials from Brown University

Record History

  1. Primary completion pushed from Jun 1, 2026 to Dec 1, 2026v5
  2. Trial status: Not Yet Recruiting to Recruiting
    • Start date changed from estimate of Sep 30, 2025 to Aug 27, 2025
    • Site details revised
    v4
  3. Start date: Jun 30, 2025 to Sep 30, 2025v3
  4. Start date: May 30, 2025 to Jun 30, 2025v2
  5. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This is a study conducted in patients with a diagnosis of stage IB-IVA squamous cell carcinoma of the head and neck. Patients will have a comprehensive geriatric assessment (CGA) as part of standard assessments. The patients classified as frail, with a CGA score of 3-5, will then be treated with a novel reduced intensity regimen. The regimen will be tailored based on the programmed cell death ligand 1 combined positive score (PD-L1 CPS) and will involve 4 cycles of systemic chemotherapy and/or immunotherapy followed by radiation treatment.
Trial Details
NCT Number NCT06998069
Lead Sponsor Brown University
Collaborators: The Miriam Hospital, Rhode Island Hospital
Conditions
(from sponsor)		 Head and Neck Neoplasms
Related terms Head and Neck Neoplasms, Squamous Cell Carcinoma of Head and Neck
Enrollment 20 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov