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Cerebellar Transcranial Alternating Current Stimulation (tACS) to Modulate Parkinson's Disease Tremor

Study acronym: tACS_PD_TR
StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 6 months later Sep 30, 2026 → Mar 31, 2027
See other at-risk trials from Universitätsklinikum Hamburg-Eppendorf

Record History

See every version on ClinicalTrials.gov ↗

  1. Primary completion pushed from Sep 30, 2026 to Mar 31, 2027
    • Study completion pushed from Dec 31, 2026 to Dec 31, 2027
    v3
  2. Primary completion date: Oct 31, 2025 to Sep 30, 2026
    • Primary endpoint revised
    • Study completion date: Dec 31, 2025 to Dec 31, 2026
    v2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Parkinson's disease (PD) is a prevalent neurodegenerative disorder characterized by different motor symptoms, including tremor, which is particularly difficult to manage. Common treatments, such as dopaminergic therapy, can have limitations in efficacy. Recent advancements in non-invasive brain stimulation, specifically phase-adaptive transcranial alternating current stimulation (tACS), offer a promising approach to reduce PD tremor. In the current project, a newly developed closed-loop system delivers precisely synchronized cerebellar tACS by aligning stimulation with the intrinsic hand tremor signal. The study will assess the efficacy of this novel approach to reduce hand tremor in PD patients.
Trial Details
NCT Number NCT06993571
Lead Sponsor Universitätsklinikum Hamburg-Eppendorf
Conditions
(from sponsor)		 Parkinson's Disease (PD), Tremor
Related terms Parkinson Disease, Tremor
Enrollment 10 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov