Clinical Trial

Neuroprotection Bundles For Comatose Survivors Following Cardiac Arrest

Study acronym: LAPTOPS
Recruiting
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Summary
The investigators designed LAPTOPS to determine the effectiveness of a goal-directed neuroprotection bundles of active management including body temperature,PaCO2,PaO2,position,Blood glucose ,blood sodium,Blood pressure and Lactate vs. usual care in adult post-cardiac arrest care. LAPTOPS is a large-scale pragmatic clinical trial to provide reliable evidence over the effectiveness of a widely applicable goal-directed care bundle in acute phase of adult post-cardiac arrest care.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-05-27; most recent amendment 2025-11-14.
Status change: Not Yet Recruiting → Recruiting 2025-11-14
Trial Details
NCT Number NCT06992843
Lead Sponsor Xiangya Hospital of Central South University
Conditions Cardiac Arrest, Post-cardiac Arrest Care
Enrollment 1,008 participants
Start Date 2025-10-22
Primary Completion 2027-08 (estimated)
Study Completion 2027-08 (estimated)
Updated on ClinicalTrials.gov 2025-11-18