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Cardiovascular Disease Prevention Strategies for High-risk Urban Sedentary Employees in Karachi, Pakistan

Study acronym: m-LIfE
StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 3 months later Jun 2026 → Oct 2026
See other at-risk trials from Aga Khan University

Record History

  1. Notable Recruitment opened Start date changed from estimate of Jan 2026 to Jun 22, 2026 · Primary completion pushed from Jun 2026 to Oct 2026 · Completion pushed from Aug 2026 to Nov 2026 · 2 morev3 Show 5 more changesShow less
    • Start date changed from estimate of Jan 2026 to Jun 22, 2026
    • Primary completion pushed from Jun 2026 to Oct 2026
    • Completion pushed from Aug 2026 to Nov 2026
    • Site details revised
    • Study description shortened, about 4 words

    See this version in full on ClinicalTrials.gov ↗

  2. Notable Start date: Oct 2025 to Jan 2026 Primary completion date: Apr 2026 to Jun 2026 · Completion date: Jun 2026 to Aug 2026 · Secondary endpoints: 5 to 1v2 Show 3 more changesShow less
    • Primary completion date: Apr 2026 to Jun 2026
    • Completion date: Jun 2026 to Aug 2026
    • Secondary endpoints: 5 to 1

    See this version in full on ClinicalTrials.gov ↗

  3. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Heart diseases and other non-communicable diseases are serious health issues in countries like Pakistan. Many people who work in offices, like bank employees, sit for more than 8 hours a day. This is called a sedentary lifestyle, and it increases the risk of heart diseases. This research project aims to find out if a newly developed context specific mobile phone application can help these sedentary employees to improve their lifestyle. The app, called m-LIfE (mHealth-based Lifestyle Intervention for Employees), will be designed to help employees to move more during the day and eat healthier food like fruits and vegetables. The study will involve bank employees in urban Karachi, Pakistan. They will be divided into two arms: Intervention arm: Participants in this arm will use the m-LIfE app for 12 weeks. They will get reminders and tips to take breaks, exercise, and eat healthy. Routine care arm: Participants in this arm will receive printed basic educational material about prevention of risk factors of heart diseases and improving lifestyle. After the 12 weeks of intervention, there will be a follow-up period at 4th week to check if participants are maintaining healthy habits. This study could help find simple and affordable ways to improve the health of office workers and reduce pressure on the healthcare system.
Trial Details
NCT Number NCT06981247
Lead Sponsor Aga Khan University
Collaborators: Fogarty International Center of the National Institute of Health
Conditions Physical Activity, Life Style, Dietary Habits, Cardiovascular Diseases
Enrollment 84 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov