Clinical Trial

Clinical Study of Combined EphA2-targeted CAR-DC and CAR-T Cell Therapy for Non-small Cell Lung Cancer

Recruiting Phase 1
View on ClinicalTrials.gov →
Record status
This record was last updated May 15, 2025 (before its estimated April 2026 completion). Its status may not reflect the trial's current state.
Summary
This is an open-label, single-arm clinical study designed to evaluate the safety and preliminary efficacy of EphA2-targeted CAR-DC combined with CAR-T cell therapy in patients with non-small cell lung cancer.
Protocol Amendment History 1 change
notable Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University -> Second Affiliated Hospital, Zhejiang University, School of Medicine 2026-08-09
Trial Details
NCT Number NCT06972576
Lead Sponsor Second Affiliated Hospital, School of Medicine, Zhejiang University
Conditions Non-Small Cell Lung Cancer
Enrollment 18 participants
Start Date 2025-05-09
Primary Completion 2026-04 (estimated)
Study Completion 2027-04 (estimated)
Updated on ClinicalTrials.gov 2025-05-15